You may also like this partner content (after ad)
Overall, diabetes affects more than 420 thousands of people of which, average in, 10% with type 1 diabetes and 80% with type 2 diabetes. Sober 2022, the diabetes has capital t the direct result in sober 1 .5 million sober dcs worldwide. Often diagnosed late, type 2 diabetes has serious long-term consequences, such as retinal damage leading to blindness, kidney failure or healing problems up to amputation. Recently, a team of American researchers showed the potential of bioelectronic medicine as an alternative or complement to drugs in the treatment of chronic illnesses, and in particular type 2 diabetes.
People with sober sober type 2 diabetes are sober with insulin, but this hormone regulates their blood sugar levels less effectively. It remains abnormally high after eating, which is the definition of diabetes. Little by little, the pancras is exhausted to secrete increasing amounts of insulin. also called fatty diabetes, or non-insulin-dependent diabetes, type 2 diabetes mainly affects people who are overweight or obese, sedentary, most often after 45 years. It represents 45% of cases sober with diabetes after 60 years.
A sober study at INSERM (National Institute of Health and Sober Medical Research) estimates that 5% of the French population (approximately 2 million people) suffer from type 2 diabetes. The number of diagnosed cases of type 2 diabetes is increasing by more than 5% each year. A component of the increase remained with the aging of the people. Another factor is an unhealthy lifestyle, nutritional imbalances and a sedentary lifestyle leading to a general increase in weight and the number of people with obesity. This is how, in Western countries, the average age of onset of type 2 diabetes has decreased: cases of adolescents with this disease have even been reported in the United States. Another subject of alert: the recent increase in “medicated diabetes”, associated in particular with certain neuroleptics.
Unfortunately, there is no cure for diabetes. The reference treatment for type 2 diabetes is the optimization of lifestyle habits: weight loss if necessary, regular body activity and a balanced diet may be sufficient to control blood sugar in the first temperature. As a second purpose, oral and/or injectable antidiabetics are prescribed to control blood sugar. When diabetes progresses, it may require the implementation of insulin treatment. But there are risks in terms of forgetting or taking too much of the treatment, inducing respectively hyperglycemia or hypoglycemia, both of which are potentially fatal.
In adults, diabetes doubles or triples the risk of myocardial infarction and stroke. Every year, among the 04 000 diabetics hospitalized put el myocardial infarction, 952 will die. Diabetic neuropathy (nerve damage) (mainly affecting the extremities) associated with decreased blood flow increases the likelihood of developing ulcers, infections and, ultimately, amputations. Moreover, each year, there are no less than 9000. In addition, diabetes is one of the main causes of kidney failure: every year, 2000 diabetics start dialysis or undergo a sober kidney transplant, according to INSERM.
It is in this context that a team led by GE Study, a General Electric powered sober branch including sober researchers from Yale College of Medicine, sober from UCLA and the Feinstein Institutes for Clinical Analysis suggests that type 2 sober diabetes may be characteristic without medication, or at least onset could be prevented and reversed using bioelectronics. Their discovery has testosterone levels published in the journal Character Biomedical Executive.
A bioelectronics at the service of the nerves
Let’s go back to what bioelectronic systems are. They refer to improvements in so-called electronic-electromagnetic-living interfaces. The latter have the ability to draw income from electrical signals, for example through implants, in order to electrically stimulate the nerves of the peripheral nervous system. They are promising for the treatment of certain chronic diseases such as arthritis, diabetes or asthma. The results reported in this new study represent an important video milestone in the field of bioelectronic medicine. nerves of the sober body focusing high frequency sound waves on specific sensory nerves in the liver. Ultrasound is known to stimulate specific neural pathways in organs (which may be associated with various illnesses). The researchers found that their treatment method using ultrasound prevented or reversed type 2 diabetes in three different preclinical models: mice, mice and pigs. A technology is called Pleasure Peripheral Focused Ultrasound (pFUS).
In a first step, UCLA researchers designed a 3D scaffold for the purpose of growing and growing neurons used in the study’s lab experiments. It learned to consist of a hydrogel with microscopic skin pores in which neurons reside and grow, providing ample space for numerous dendrites and axons to connect neurons together. The researchers adjusted the stiffness of the scaffold to the optimal circumstances for the neurons and added small chains of amino acids (peptides) that the nerve cells can adhere to.
This is how experiments inside vitro have shown that neurons can be activated and send signals when stimulated by ultrasound, due to the presence of sensors on the surface of the cells. These sensors react to ultrasound-induced pressure changes. in a press release: Our studies indicate that focused ultrasound activates neurons via ion channels sensitive to mechanical effects. This is a whole new way to interface with our body and treat diseases.
” data-image-title=”technique-ultrasons-canaux-ioniques-foie” data-large-file=”https://trustmyscience.com/wp-content/uploads/2022/04/technique-ultrasons-canaux-ioniques-foie.png” data-lazy-sizes=”(max-width: 600px) 100vw, 600px” data-lazy-src=”https://trustmyscience.com/wp-content/uploads/2022/04/technique-ultrasons-canaux-ioniques-foie.png” data-lazy-srcset=”https://trustmyscience.com/wp-content/uploads/2022/04/technique-ultrasons-canaux-ioniques-foie.png 600w, https://trustmyscience.com/wp-content/uploads/2022/04/technique-ultrasons-canaux-ioniques-foie-300×151.png 300w, https://trustmyscience.com/wp-content/uploads/2022/04/technique-ultrasons-canaux-ioniques-foie-500×251.png 500w, https://trustmyscience.com/wp-content/uploads/2022/04/technique-ultrasons-canaux-ioniques-foie-472×237.png 472w, https://trustmyscience.com/wp-content/uploads/2022/04/technique-ultrasons-canaux-ioniques-foie-390×196.png 390w” data-medium-file=”https://trustmyscience.com/wp-content/uploads/2022/04/technique-ultrasons-canaux-ioniques-foie-300×151.png” data-orig-file=”https://trustmyscience.com/wp-content/uploads/2022/04/technique-ultrasons-canaux-ioniques-foie.png” data-orig-size=”600,301″ data-permalink=”https://trustmyscience.com/traitement-diabete-type-2-ultrasons-bioelectronique/technique-ultrasons-canaux-ioniques-foie/” height=”301″ src=”data:image/svg+xml,%3Csvg%20xmlns=’http://www.w3.org/2000/svg’%20viewBox=’0%200%20600%20301’%3E%3C/svg%3E” width=”600″>
In the second range temperature, experiments in vivo were performed on three preclinical animal models. Specifically, the researchers explain in the research briefing posted at Character
Ultrasounds, sober hope treatment still trying
As pointed out in a press release by Raimund Herzog, a sober endocrinologist at Yale College of Medicine working on the project: Unfortunately, he nyc currently only very few sober drugs lower insulin levels which. Since our ongoing clinical trials confirm the promise of the preclinical studies reported in this article, and that ultrasound can be used to lower both insulin and sugar levels, ultrasound neuromodulation would be an exciting and entirely new addition to treatment options. current put our patients.
Indeed, the study revealed that only three Minutes of focused ultrasound each day were sufficient to maintain normal blood sugar levels in a diabetic mouse. Captain christopher Puleo, biomedical engineer at GE Analysis who co-directed the diabetes studies and corresponding author of the Character Biomedical Anatomist, says: We have shown that ultrasound can be used to prevent or reverse diabetes in these preclinical studies. . We are now in the middle of human feasibility trials with a group of subjects with type 2 diabetes, which brings our work to a clinical translation